Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation

Figure 5

Diminished cytokine and chemokine expression in TSLPR^−/− mice in innate type of lung inflammation induced by papain. IL-1𝛽, IL-13, IL-33, TSLP, CCL11 (Eotaxin-1), CCL17 (TARC), CCL22 (MDC), and CCL24 (Eotaxin-2) in the lung homogenate after papain exposure were determined by ELISA (a–h). These experiments were performed twice (𝑛=8 mice per group). One representative experiment is shown. Values are the mean ± SEM of 8 mice per group.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)