Table of Contents
ISRN Polymer Science
Volume 2014 (2014), Article ID 128154, 6 pages
http://dx.doi.org/10.1155/2014/128154
Research Article

Preparation and Drug-Release Kinetics of Porous Poly(L-lactic acid)/Rifampicin Blend Particles

Department of Materials Science and Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910 8507, Japan

Received 29 November 2013; Accepted 18 January 2014; Published 23 February 2014

Academic Editors: C. Bernal, A. Granville, D. Pavel, J. Puiggali, A. V. Raghu, A. Uygun, and A. Varesano

Copyright © 2014 Takashi Sasaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Freiberg and X. X. Zhu, “Polymer microspheres for controlled drug release,” International Journal of Pharmaceutics, vol. 282, no. 1-2, pp. 1–18, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. D. Lensen, K. van Breukelen, D. M. Vriezema, and J. C. M. van Hest, “Preparation of biodegradable liquid core PLLA microcapsules and hollow PLLA microcapsules using microfluidics,” Macromolecular Bioscience, vol. 10, no. 5, pp. 475–480, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. A. El Fagui and C. Amiel, “PLA nanoparticles coated with a beta-cyclodextrin polymer shell: preparation, characterization and release kinetics of a hydrophobic compound,” International Journal of Pharmaceutics, vol. 436, pp. 644–651, 2012. View at Google Scholar
  4. S. Zhou, X. Deng, M. Yuan, and X. Li, “Investigation on preparation and protein release of biodegradable polymer microspheres as drug-delivery system,” Journal of Applied Polymer Science, vol. 84, no. 4, pp. 778–784, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. U. Paiphansiri, P. Tangboriboonrat, and K. Landfester, “Polymeric nanocapsules containing an antiseptic agent obtained by controlled nanoprecipitation onto water-in-oil miniemulsion droplets,” Macromolecular Bioscience, vol. 6, no. 1, pp. 33–40, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Mao, C. Guo, Y. Shi, and L. C. Li, “Recent advances in polymeric microspheres for parenteral drug delivery. Part 1,” Expert Opinion Drug Delivery, vol. 9, pp. 1161–1176, 2012. View at Google Scholar
  7. S. Mao, C. Guo, Y. Shi, and L. C. Li, “Recent advances in polymeric microspheres for parenteral drug delivery. Part 2,” Expert Opinion Drug Delivery, vol. 9, pp. 1209–1223, 2012. View at Google Scholar
  8. R. T. Liggins and H. M. Burt, “Paclitaxel loaded poly(L-lactic acid) microspheres: properties of microspheres made with low molecular weight polymers,” International Journal of Pharmaceutics, vol. 222, no. 1, pp. 19–33, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. R. T. Liggins and H. M. Burt, “Paclitaxel loaded poly(L-lactic acid) (PLLA) microspheres. II. The effect of processing parameters on microsphere morphology and drug release kinetics,” International Journal of Pharmaceutics, vol. 281, no. 1-2, pp. 103–106, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. Z. Wang, “Effects of the process parameters on the initial burst release of poly(lactide-co-glycolide) microspheres containing bovine serum albumin by the double-emulsion solvent evaporation/extraction method,” Journal of Applied Polymer Science, vol. 115, no. 5, pp. 2599–2608, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Sasaki, K. Tanaka, D. Morino, and K. Sakurai, “Morphology and release kinetics of protein-loaded porous poly(L-lactic acid) spheres prepared by freeze-drying technique,” ISRN Pharmaceutics, vol. 2011, Article ID 490567, 8 pages, 2011. View at Publisher · View at Google Scholar
  12. A. Bohr, M. Yang, S. Baldursdottir et al., “Particle formation and characteristics of Celecoxib-loaded poly(lactic-co-glycolic acid) microparticles prepared in different solvents using electrospraying,” Polymer, vol. 53, pp. 3220–3229, 2012. View at Google Scholar
  13. Y. Baimark and M. Srisa-Ard, “Preparation of drug-loaded microspheres of linear and star-shaped poly(D,L-lactide)s and their drug release behaviors,” Journal of Applied Polymer Science, vol. 124, no. 5, pp. 3871–3878, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. W. Zheng and S. L. Simon, “Polystyrene freeze-dried from dilute solution: Tg depression and residual solvent effects,” Polymer, vol. 47, no. 10, pp. 3520–3527, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Sasaki, D. Morino, and N. Tabata, “Origin of enhanced cold crystallization rate for freeze-dried poly(L-lactide) from solutions,” Polymer Engineering and Science, vol. 51, no. 9, pp. 1858–1865, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Sasaki, N. Yamauchi, S. Irie, and K. Sakurai, “Differential scanning calorimetry study on thermal behaviors of freeze-dried poly(L-lactide) from dilute solutions,” Journal of Polymer Science B, vol. 43, no. 2, pp. 115–124, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. E. W. Fischer, H. J. Sterzel, and G. Wegner, “Investigation of the structure of solution grown crystals of lactide copolymers by means of chemical reactions,” Kolloid-Zeitschrift und Zeitschrift für Polymere, vol. 251, no. 11, pp. 980–990, 1973. View at Publisher · View at Google Scholar · View at Scopus
  18. P. L. Ritger and N. A. Peppas, “A simple equation for desciption of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs,” Journal of Controlled Release, vol. 5, no. 1, pp. 23–36, 1987. View at Google Scholar · View at Scopus