Neuroprotective Effect of Ethanol Extract of Leaves of Malva parviflora against Amyloid-β- (Aβ-) Mediated Alzheimer’s Disease
Table 1
Effect of ethanol extract of leaves of Malva parviflora on enzymes of mouse brain.
Enzymes
Group I
Group II
Group III
Group IV
Glutathione peroxidase (GSHx)
109.7 ± 5.3
63.8 ± 6.2*
106.3 ± 5.3**
107.0 ± 8.4**
(nmol GSH oxidized/mg protein)
Glutathione reductase (GSHr)
6.2 ± 1.03
2.4 ± 0.6*
5.5 ± 0.8**
6.8 ± 0.6**
(NADPH oxidized/min/mg protein)
Catalase
58.1 ± 0.71
37.3 ± 0.6*
57.2 ± 0.9**
58.8 ± 0.4**
(nmol H2O2 decomposed/min/min protein)
Superoxide dismutase
6.7 ± 0.73
2.7 ± 0.3*
6.1 ± 0.6**
6.2 ± 0.5**
(Units/min/mg protein)
Lipid peroxidase
2.4 ± 0.1
4.3 ± 0.2*
2.0 ± 0.3**
2.3 ± 0.4**
(nmol MDA/mg protein)
The values are mean ± SEM. . , significant difference when compared to normal control mice. , significant difference when compared to Alzheimer group mice (One-way ANOVA followed by Tukey’s post hoc test).
