Table of Contents
ISRN Infectious Diseases
Volume 2014 (2014), Article ID 208072, 8 pages
http://dx.doi.org/10.1155/2014/208072
Review Article

Necrotizing Fasciitis: Diagnostic Challenges and Current Practices

Department of General Surgery, Victoria Hospital, Bangalore Medical College and Research Institute, Bangalore, Karnataka 560002, India

Received 12 November 2013; Accepted 5 December 2013; Published 22 January 2014

Academic Editors: E. Çiftçi and R. Favory

Copyright © 2014 Abhishek Vijayakumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Jones, “Surgical memoirs of the war of the rebellion: investigation upon the nature, causes and treatment of hospital gangrene as prevailed in the Confederate armies 1861–1865,” US Sanitary Commission, New York, NY, USA, 1871.
  2. N. Eke, “Fournier's gangrene: a review of 1726 cases,” British Journal of Surgery, vol. 87, no. 6, pp. 718–728, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. F. Meleney, “Hemolytic streptococcus gangrene,” Archives of Surgery, vol. 9, pp. 317–364, 1924. View at Google Scholar
  4. B. Wilson, “Necrotizing fasciitis,” The American Surgeon, vol. 18, no. 4, pp. 416–431, 1952. View at Google Scholar · View at Scopus
  5. A. F. Hefny, H. O. Eid, M. Al-Hussona, K. M. Idris, and F. M. Abu-Zidan, “Necrotizing fasciitis: a challenging diagnosis,” European Journal of Emergency Medicine, vol. 14, no. 1, pp. 50–52, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. C.-H. Wong, H.-C. Chang, S. Pasupathy, L.-W. Khin, J.-L. Tan, and C.-O. Low, “Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality,” Journal of Bone and Joint Surgery A, vol. 85, no. 8, pp. 1454–1460, 2003. View at Google Scholar · View at Scopus
  7. C. R. Baxter, “Surgical management of soft tissue infections,” Surgical Clinics of North America, vol. 52, no. 6, pp. 1483–1499, 1972. View at Google Scholar · View at Scopus
  8. R. Lewis, “Necrotizing soft tissue infections,” in Surgical Infections in Critical Care Medicine, J. L. Meakins, Ed., pp. 153–171, Churchill Livingstone, London, UK, 20th edition, 1985. View at Google Scholar
  9. N. Forbes and A. P. Nigel Rankin, “Necrotizing fasciitis and non steroidal anti-inflammatory drugs: a case series and review of the literature,” New Zealand Medical Journal, vol. 114, no. 1124, pp. 3–6, 2001. View at Google Scholar · View at Scopus
  10. W. Tung-Yiu, H. Jehn-Shyun, C. Ching-Hung, and C. Hung-An, “Cervical necrotizing fasciitis of odontogenic origin: a report of 11 cases,” Journal of Oral and Maxillofacial Surgery, vol. 58, no. 12, pp. 1347–1352, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Clark, D. Davidson, M. Letts, L. Lawton, and A. Jawadi, “Necrotizing fasciitis secondary to chickenpox infection in children,” Canadian Journal of Surgery, vol. 46, no. 1, pp. 9–14, 2003. View at Google Scholar · View at Scopus
  12. S. Frick and A. Cerny, “Necrotizing fasciitis due to Streptococcus pneumoniae after intramuscular injection of nonsteroidal anti-inflammatory drugs: report of 2 cases and review,” Clinical Infectious Diseases, vol. 33, no. 5, pp. 740–744, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. L. G. Svensson, A. J. Brookstone, and M. Wellsted, “Necrotizing fasciitis in contused areas,” Journal of Trauma, vol. 25, no. 3, pp. 260–262, 1985. View at Google Scholar · View at Scopus
  14. B. J. Childers, L. D. Potyondy, R. Nachreiner et al., “Necrotizing fasciitis: a fourteen-year retrospective study of 163 consecutive patients,” American Surgeon, vol. 68, no. 2, pp. 109–116, 2002. View at Google Scholar · View at Scopus
  15. D. L. Stevens, “Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance the progression of bacterial infections to toxic shock syndrome?” Clinical Infectious Diseases, vol. 21, no. 4, pp. 977–980, 1995. View at Google Scholar · View at Scopus
  16. D. M. Aronoff and K. C. Bloch, “Assessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A streptococcus,” Medicine, vol. 82, no. 4, pp. 225–235, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. C.-T. Hsiao, H.-H. Weng, Y.-D. Yuan, C.-T. Chen, and I.-C. Chen, “Predictors of mortality in patients with necrotizing fasciitis,” American Journal of Emergency Medicine, vol. 26, no. 2, pp. 170–175, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. D. Elliott, J. A. Kufera, and R. A. M. Myers, “The microbiology of necrotizing soft tissue infections,” American Journal of Surgery, vol. 179, no. 5, pp. 361–366, 2000. View at Publisher · View at Google Scholar · View at Scopus
  19. E. K. Chapnick and E. I. Abter, “Necrotizing soft-tissue infections,” Infectious Disease Clinics of North America, vol. 10, no. 4, pp. 835–855, 1996. View at Publisher · View at Google Scholar · View at Scopus
  20. T. L. Bosshardt, V. J. Henderson, and C. H. Organ Jr., “Necrotizing soft-tissue infections,” Archives of Surgery, vol. 131, no. 8, pp. 846–854, 1996. View at Google Scholar · View at Scopus
  21. M. K. Hill and C. V. Sanders, “Necrotizing and gangrenous soft tissue infections,” in The Skin and Infection: A Color Atlas and Text, C. V. Sanders and L. T. Nesbitt Jr, Eds., pp. 62–75, Lipincott, Williams & Wilkins, Baltimore, Md, USA, 1995. View at Google Scholar
  22. R. J. Green, D. C. Dafoe, and T. A. Raffin, “Necrotizing fasciitis,” Chest, vol. 110, no. 1, pp. 219–229, 1996. View at Google Scholar · View at Scopus
  23. A. J. Headley, “Necrotizing soft tissue infections: a primary care review,” American Family Physician, vol. 68, no. 2, pp. 323–328, 2003. View at Google Scholar · View at Scopus
  24. C.-T. Hsiao, L.-J. Lin, C.-J. Shiao, K.-Y. Hsiao, and I.-C. Chen, “Hemorrhagic bullae are not only skin deep,” American Journal of Emergency Medicine, vol. 26, no. 3, pp. 316–319, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. L. A. Sudarsky, J. C. Laschinger, G. F. Coppa, and F. C. Spencer, “Improved results from a standardized approach in treating patients with necrotizing fasciitis,” Annals of Surgery, vol. 206, no. 5, pp. 661–665, 1987. View at Google Scholar · View at Scopus
  26. Y.-S. Wang, C.-H. Wong, and Y.-K. Tay, “Staging of necrotizing fasciitis based on the evolving cutaneous features,” International Journal of Dermatology, vol. 46, no. 10, pp. 1036–1041, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. D. C. Elliott, J. A. Kufera, and R. A. M. Myers, “Necrotizing soft tissue infections: risk factors for mortality and strategies for management,” Annals of Surgery, vol. 224, no. 5, pp. 672–683, 1996. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Dufel and M. Martino, “Simple cellulitis or a more serious infection?” Journal of Family Practice, vol. 55, no. 5, pp. 396–400, 2006. View at Google Scholar · View at Scopus
  29. M. N. Mallikarjuna, A. Vijayakumar, V. S. Patil, and B. S. Shivswamy, “Fournier’s gangrene: current practices,” ISRN Surgery, vol. 2012, Article ID 942437, 8 pages, 2012. View at Publisher · View at Google Scholar
  30. D. B. Wall, S. R. Klein, S. Black, and C. De Virgilio, “A simple model to help distinguish necrotizing fasciitis from nonnecrotizing soft tissue infection,” Journal of the American College of Surgeons, vol. 191, no. 3, pp. 227–231, 2000. View at Publisher · View at Google Scholar · View at Scopus
  31. C.-H. Wong, L.-W. Khin, K.-S. Heng, K.-C. Tan, and C.-O. Low, “The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections,” Critical Care Medicine, vol. 32, no. 7, pp. 1535–1541, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. Y.-J. Lim, F.-C. Yong, C.-H. Wong, and A. B. H. Tan, “Necrotising fasciitis and traditional medical therapy—a dangerous liaison,” Annals of the Academy of Medicine Singapore, vol. 35, no. 4, pp. 270–273, 2006. View at Google Scholar · View at Scopus
  33. M. G. Wysoki, T. A. Santora, R. M. Shah, and A. C. Friedman, “Necrotizing fasciitis: CT characteristics,” Radiology, vol. 203, no. 3, pp. 859–863, 1997. View at Google Scholar · View at Scopus
  34. M. R. Schmid, T. Kossmann, and S. Duewell, “Differentiation of necrotizing fasciitis and cellulitis using MR imaging,” American Journal of Roentgenology, vol. 170, no. 3, pp. 615–620, 1998. View at Google Scholar · View at Scopus
  35. A. Arslan, C. Pierre-Jerome, and A. Borthne, “Necrotizing fasciitis: unreliable MRI findings in the preoperative diagnosis,” European Journal of Radiology, vol. 36, no. 3, pp. 139–143, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. J. Fildes, M. P. Bannon, and J. Barrett, “Soft-tissue infections after trauma,” Surgical Clinics of North America, vol. 71, no. 2, pp. 371–384, 1991. View at Google Scholar · View at Scopus
  37. I. Stamenkovic and P. D. Lew, “Early recognition of potentially fatal necrotizing fasciitis. The use of frozen-section biopsy,” New England Journal of Medicine, vol. 310, no. 26, pp. 1689–1693, 1984. View at Google Scholar · View at Scopus
  38. J. Majeski and E. Majeski, “Necrotizing fasciitis: improved survival with early recognition by tissue biopsy and aggressive surgical treatment,” Southern Medical Journal, vol. 90, no. 11, pp. 1065–1068, 1997. View at Google Scholar · View at Scopus
  39. D. B. Diercks, N. Kuppermann, R. W. Derlet, and A. A. Ernst, “Derivation and validation of a model for the need of hospital admission in patients with extremity cellulitis,” Academic Emergency Medicine, vol. 7, no. 5, p. 562, 2000. View at Google Scholar
  40. D. L. Stevens, A. L. Bisno, H. F. Chambers et al., “Practice guidelines for the diagnosis and management of skin and soft-tissue infections,” Clinical Infectious Diseases, vol. 41, no. 10, pp. 1373–1406, 2005. View at Publisher · View at Google Scholar · View at Scopus
  41. J. D. Cunningham, L. Silver, and D. Rudikoff, “Necrotizing fasciitis: a plea for early diagnosis and treatment,” Mount Sinai Journal of Medicine, vol. 68, no. 4-5, pp. 253–261, 2001. View at Google Scholar · View at Scopus
  42. J. A. Majeski and J. W. Alexander, “Early diagnosis, nutritional support, and immediate exensive debridement improvesurvival in necrotizing fasciitis,” American Journal of Surgery, vol. 145, no. 6, pp. 784–787, 1983. View at Google Scholar · View at Scopus
  43. J. Darenberg, N. Ihendyane, J. Sjölin et al., “Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome: a European randomized, double-blind, placebo-controlled trial,” Clinical Infectious Diseases, vol. 37, no. 3, pp. 333–340, 2003. View at Publisher · View at Google Scholar · View at Scopus
  44. R. Kaul, A. McGeer, D. E. Low et al., “Population-based surveillance for group A streptococcal necrotiziug fasciitis: clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases,” American Journal of Medicine, vol. 103, no. 1, pp. 18–24, 1997. View at Publisher · View at Google Scholar · View at Scopus
  45. B. D. Bilton, G. B. Zibari, R. W. McMillan, D. F. Aultman, G. Dunn, and J. C. McDonald, “Aggressive surgical management of necrotizing fasciitis serves to decrease mortality: a retrospective study,” American Surgeon, vol. 64, no. 5, pp. 397–401, 1998. View at Google Scholar · View at Scopus
  46. S. T. Lille, T. T. Sato, L. H. Engrav, H. Foy, and G. J. Jurkovich, “Necrotizing soft tissue infections: obstacles in diagnosis,” Journal of the American College of Surgeons, vol. 182, no. 1, pp. 7–11, 1996. View at Google Scholar · View at Scopus
  47. J. A. Riseman, W. A. Zamboni, A. Curtis, D. R. Graham, H. R. Konrad, and D. S. Ross, “Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements,” Surgery, vol. 108, no. 5, pp. 847–850, 1990. View at Google Scholar · View at Scopus
  48. A. Shupak, O. Shoshani, I. Goldenberg, A. Barzilai, R. Moskuna, and S. Bursztein, “Necrotizing fasciitis: an indication for hyperbaric oxygenation therapy?” Surgery, vol. 118, no. 5, pp. 873–878, 1995. View at Publisher · View at Google Scholar · View at Scopus
  49. D. R. Brown, N. L. Davis, M. Lepawsky, J. Cunningham, and J. Kortbeek, “A multicenter review of the treatment of major truncal necrotizing infections with and without hyperbaric oxygen therapy,” American Journal of Surgery, vol. 167, no. 5, pp. 485–489, 1994. View at Publisher · View at Google Scholar · View at Scopus
  50. M. Harris and D. Young, “Hyperbaric medicine. A specialized mode of treatment that is gaining acceptance,” Indiana Medicine, vol. 80, no. 3, pp. 258–261, 1987. View at Google Scholar · View at Scopus
  51. C. R. McHenry, J. J. Piotrowski, D. Petrinic et al., “Determinants of mortality for necrotizing soft-tissue infections,” Annals of Surgery, vol. 221, no. 5, pp. 558–565, 1995. View at Google Scholar · View at Scopus
  52. B. W. Frazee, C. Fee, J. Lynn et al., “Community-acquired necrotizing soft tissue infections: a review of 122 cases presenting to a single emergency department over 12 years,” Journal of Emergency Medicine, vol. 34, no. 2, pp. 139–146, 2008. View at Publisher · View at Google Scholar · View at Scopus
  53. A. T. Miller, P. Saadai, A. Greenstein, and C. M. Divino, “Postprocedural necrotizing fasciitis: a 10-year retrospective review,” American Surgeon, vol. 74, no. 5, pp. 405–409, 2008. View at Google Scholar · View at Scopus
  54. O. Oncul, C. Erenoglu, C. Top et al., “Necrotizing fasciitis: a life-threatening clinical disorder in uncontrolled type 2 diabetic patients,” Diabetes Research and Clinical Practice, vol. 80, no. 2, pp. 218–223, 2008. View at Publisher · View at Google Scholar · View at Scopus
  55. D. A. Anaya, K. McMahon, A. B. Nathens, S. R. Sullivan, H. Foy, and E. Bulger, “Predictors of mortality and limb loss in necrotizing soft tissue infections,” Archives of Surgery, vol. 140, no. 2, pp. 151–157, 2005. View at Publisher · View at Google Scholar · View at Scopus