Table of Contents
International Scholarly Research Notices
Volume 2014, Article ID 250913, 6 pages
http://dx.doi.org/10.1155/2014/250913
Research Article

Predictors of Survival in HIV-Infected Patient after Initiation of HAART in Zewditu Memorial Hospital, Addis Ababa, Ethiopia

1Federal HAPCO, P.O. Box 57101, Ethiopia
2Ethiopian Public Health Association, P.O. Box 7117, Ethiopia
3School of Public Health, College of Health Science, Addis Ababa University, P.O. Box 25819/1000, Ethiopia

Received 15 March 2014; Accepted 16 July 2014; Published 9 October 2014

Academic Editor: Gabriella D’ettorre

Copyright © 2014 Shibre Mengesha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. ART has improved the survival of HIV-infected patients. However, patients in resource-poor countries have higher mortality rates, particularly the first months after initiating ART. In this study we tried to determine the survival factors in HIV-infected patients treated with HAART in Zewditu Memorial Hospital. Methods. A retrospective cohort study was conducted from 2008 to 2012. All HIV-infected patients above the age of 14 took first line ART. Data were collected, entered, and analyzed using Epi Info 7 and SPSS Version 20. Life table was used to estimate mortality after initiation of ART, and Kaplan-Meier was used to compare survival curves. Cox proportional hazards model was used to assess the predictors of mortality. Results. The incidence of mortality was 3.8/100 person-years. Independent predictors of mortality were WHO clinical stages 3-4 ( at 95% CI (1.26, 5.31)), anemia (hemoglobin level < 10 gm/dL ( at 95% CI (2.58, 11.86)). Conclusion. Incidence of mortality was found relatively low, majority of deaths occurring within 3 months of starting ART. WHO stages 3-4, anemia (hemoglobin count < 10 gm/dL), and past TB coinfection were the main predictors of mortality. The underlying causes for early death in patients presenting at late stages should be investigated.