Table 3: Genotypes of some common structural variants.

Abnormal variantsGenotype

Hb Ebeta26(B8)Glu → Lys, GAG → AAG
Hb D Punjabbeta121(GH4)Glu → Gln, GAA → CAA
Hb Sbeta6(A3)Glu → Val, GAG → GTG
Hb D Iranbeta22Glu → Gln, GAA → CAA
Hb Hopebeta136(H14)Gly → Asp (GGT → GAT)
Hb OArabbeta121(GH4)Glu → Lys, (GAA → AAA)
Hb Cbeta6(A3)Glu → Lys, GAG → AAG
Hb J Meerutalpha120(H3)Ala → Glu, GCG → GAG
Hb Q Indiaalpha64(E13)Asp → His, GAC → CAC