Potential Interaction of Green Tea Extract with Hydrochlorothiazide on Diuretic Activity in Rats

Table 3

Effect on percentage saline load excretion and diuretic action.

Treatment	Percentage of saline load excreted	Diuretic action	Diuretic activity
Normal control	61.65 ± 2.92	1.34	—
HCTZ	136.91 ± 4.39^***	3.10^***	—
GTE-100	86.28 ± 3.71^*	1.89^*	0.60
GTE-500	95.34 ± 3.27^*	2.35^*	0.75
GTE-100 + HCTZ	147.19 ± 5.11^***	3.36^***	1.08
GTE-500 + HCTZ	161.64 ± 5.16^***#	3.97^***#	1.28

All values are mean ± SEM, , , when compared to normal control; compared to HCTZ. GTE-100 (green tea extract, 100 mg/kg), GTE-500 (green tea extract, 500 mg/kg), and HCTZ (hydrochlorothiazide, 10 mg/kg).