Table of Contents
International Scholarly Research Notices
Volume 2014, Article ID 307064, 7 pages
Review Article

Disease Modifying Therapy in Multiple Sclerosis

Internal Medicine Department, University of Calabar, Calabar 540242, Cross River State, Nigeria

Received 12 March 2014; Revised 7 May 2014; Accepted 7 May 2014; Published 7 July 2014

Academic Editor: Cristoforo Comi

Copyright © 2014 U. E. Williams et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammatory demyelination and axonal degeneration. It is the commonest cause of permanent disability in young adults. Environmental and genetic factors have been suggested in its etiology. Currently available disease modifying drugs are only effective in controlling inflammation but not prevention of neurodegeneration or accumulation of disability. Search for an effective neuroprotective therapy is at the forefront of multiple sclerosis research.