Clinical Study

Impact of Comorbidity, Race, and Marital Status in Men Referred for Prostate Biopsy with PSA >20 ng/mL: A Pilot Study in High-Risk Patients

Table 2

Predictors of OS among men with positive biopsy#.

HR (95% CI)-value

CCI1.52 (1.19, 1.94)0.001
African American versus Caucasian 1.42 (0.47, 4.36)0.53
SDW versus married0.59 (0.23, 1.54)0.28
Gleason score*2.04 (1.17, 3.56)0.01
Log-transformed PSA1.62 (1.09, 2.42)0.02
Age (years)0.96 (0.91, 1.01)0.15

HR: hazard ratio, SDW: single/divorced/widowed, PSA: prostate-specific antigen, CCI: Charlson Comorbidity Index.
#Cox proportional hazards model—adjusted for PSA (log-transformed), race, age, and BMI.
*Introduced as a discrete variable in the model.