Effect of 82% Lactic Acid in Treatment of Melasma

Table 3

Total number of patients in grades I, II, and III of melisma severity scale at different durations.

		0 weeks	2 weeks	4 weeks	6 weeks	8 weeks	10 weeks	12 weeks	16 weeks	20 weeks	24 weeks
Grade 1	Number of pt	5	6	10	15*	16*	16*	16*	16*	16*	16*
	% of pt	25%	30%	50%	75%	80%	80%	80%	80%	80%	80%
	𝑃 value		0.683	0.114	0.0098	0.006	0.006	0.006	0.006	0.006	0.006
Grade 2	Number of pt	13	13	9	4*	3*	3*	3*	3*	3*	3*
	% of pt	65%	65%	45%	20%	15%	15%	15%	15%	15%	15%
	𝑃 value		1	0.267	0.013	0.0055	0.0055	0.0055	0.0055	0.0055	0.0055
Grade 3	Number of pt	2	1	1	1	1	1	1	1	1	1
	% of pt	10%	5%	5%	5%	5%	5%	5%	5%	5%	5%
	𝑃 value		0.479	0.479	0.479	0.479	0.479	0.479	0.479	0.479	0.479

𝑃 value refers to change in the number of patients at different intervals compared to “0” week, ^∗𝑃 value < 0.05.