Review Article

Primary Synovial Sarcomas of the Mediastinum: A Systematic Review and Pooled Analysis of the Published Literature

Table 3

Univariate analysis for the 30 cases of mediastinal synovial sarcoma with available follow-up data.

VariableNumber (%)MS (months)5-year OSLog-Rank value

Age
 ≥20 years24 (80%)3839.9%0.32
 <20 years6 (20%)2431.3%

Gender
 Male24 (80%)Unreached56.2%0.91
 Female6 (20%)36 months0%

Pericardial effusion
 Yes4 (13%)Unreached67%0.83
 No26 (87%)36 months29%

Histologic subtype
 Monophasic10 (33%)24 months0%0.11
 Biphasic10 (33%)36 months50.0%
 ND 10 (33%)

Size
 <10 cm8 (26%)Unreached75%0.36
 ≥10 cm11 (37%)36 months26%
 ND 11 (37%)

Surgery
 Complete resection17 (57%)Unreached63%0.003
 Incomplete13 (43%)13 months0%

Chemotherapy
 Yes14 (47%)36 months46%0.31
 No16 (53%)24 months24%

Radiotherapy
 Yes14 (47%)36 months21%0.89
 No16 (53%)unreached53%

Location in mediastinum
 Anterior/middle22 (74%)36 months39%0.93
 Posterior4 (13%)6 months50%
 ND4 (13%)

MS: median survival; OS: overall survival; ND: no data.