Lung Volume Reduction Surgery for Emphysema Treatment: State-of-the-Art and Perspectives

Table 2

Perioperative results of randomized studies on LVRS.

First; author	Year	Total/; surgical; arm (𝑁)	Surgical; approach	LVRS; method	LVRS; extension	Operative; mortality; (%)	Morbidity; (%)	Hospital stay; (mean)
Criner [14]	1999	37/32	MS	Resectional	Bilateral	9.4	15.6^M	—
Geddes [15]	2000	48/23	MS/VATS	Resectional	Bilateral	17	22^A	19
Pompeo [16]	2000	60/30	VATS	Resectional	Unilateral/bilateral	3.3	53^A	13.6
Goldstein [17]	2003	55/28	VATS/MS	Resectional	Bilateral/unilateral	7.1	14.2^M	—
DeCamp Jr [22]	2008	1218/608	MS/VATS	Resectional	Bilateral	5.2	58.7^A	—
Hillerdal [18]	2005	105/49	MS/VATS	Resectional	Bilateral	12	—	—
Miller [19]	2006	93/54	MS/VATS	Resectional	Bilateral	1.5	—	12–22
Pompeo [20]	2012	63/31*	VATS	Resectional	Unilateral	3.2	48.3^A	7.5°
		63/32*	AVATS	Nonresectional	Unilateral	0	18.7^A	6°

LVRS: lung volume reduction; MS: median sternotomy; MS: median sternotomy; VATS: video-assisted thoracic surgery; AVATS: awake VATS; *both arms were surgical. ^AAll events; ^Mmajor morbidity; °median value.