Review Article
Lung Volume Reduction Surgery for Emphysema Treatment: State-of-the-Art and Perspectives
Table 5
Results of bronchoscopic lung volume reduction.
| Technique
and first
author | Treated
patients
() | Mortality
(%) | Maximal
follow-up (months) | FEV1
(%increase) | FVC
(%increase) | RV
(%decrease) | 6MWT
(%increase) | Quality of life
(SGRQ score decrease) |
| | Valves (Zephyr) | | | | | | | | | | Sciurba [32] | 220 | 0.9 | 6 | 4.3 | NA | NA | 2.5 | 2.8 | | Herth [136] | 111 | 0.9 | 12 | 6 | NA | NA | NB | NB | | Valves (IBV) | | | | | | | | | | Sterman [137] | 91 | 2.2 | 12 | NB | NB | NB | 5.9 | 8.7 | | Sealants | | | | | | | | | | Criner [33] | 50 (28L–22H) | — | 6 | 6.7–15.6 | 5.1–9.1 | 7.1–9.0 | 7–3.4 | 6.9–9–7 | | Herth [144] | 21 | — | 6 | 11.4 | 15.5 | NB | NB | 7.5 | | Coils | | | | | | | | | | Slebos [145] | 12 | — | 6 | 14.9 | 13.4 | 11.4 | 32.9 | 14.9 | | Vapor | | | | | | | | | | Snell [36] | 11 | | 6 | NB | NB | NB | NB | 15.3 | | Snell [146] | 44 | 2 | 6 | 17 | 11 | 6 | 3 | 14 | | Airway Bypass | | | | | | | | | | Shah [149] | 208 | 0.5 | 12 | NB | NB | NB | NB | NB |
|
|
COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; VC: vital capacity; RV: residual volume; 6MWT: 6-minute walking test; SGRQ: St.George questionnaire; NA: not assessed; NB: no benefit; Llow dose; Hhigh dose.
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