Table of Contents
ISRN Virology
Volume 2014 (2014), Article ID 463173, 7 pages
http://dx.doi.org/10.1155/2014/463173
Research Article

Molecular Phylogeny of Suid Herpesvirus 1

1Laboratório de Biologia Molecular, Laboratório Nacional Agropecuário – Lanagro/MG, Ministério da Agricultura, Pecuária e Abastecimento, Avenida Rômulo Joviano s/n, Fazenda Modelo, 33600-000 Pedro Leopoldo, MG, Brazil
2Escola de Veterinária, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627, Pampulha, 31270-901 Belo Horizonte, MG, Brazil

Received 12 September 2013; Accepted 8 January 2014; Published 10 April 2014

Academic Editors: M. Magnani, S. Pöhlmann, D. Shukla, and A. Vallinoto

Copyright © 2014 Antônio A. Fonseca Jr. et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Pseudorabies is a disease that significantly impacts the swine industry. This disease is caused by Suid Herpesvirus 1 (SuHV-1), which is a double-stranded DNA virus that belongs to the Herpesviridae family and the Alphaherpesvirinae subfamily and exhibits a slow rate of genetic evolution. The aim of this study was to use both full and partial sequences of SuHV-1 genes available in GenBank to examine the evolution and divergence of viruses isolated in different parts of the world. Partial and complete sequences of SuHV-1 genes were obtained either from GenBank (i.e., us6, us7, us8, us9, ul14, ul49.5, and ul44) or from genetic sequencing of Brazilian SuHV-1 samples. The results of this study corroborate previous phylogenetic studies of SuHV-1 that demonstrated different evolutionary profiles of isolates from different parts of the globe, with a rapid genetic dispersion of Chinese isolates. All of the phylogenetic trees generated in this study demonstrated a large genetic distance between SuHV-1 isolates from the Western and Eastern regions of the world.