Table of Contents
ISRN Nephrology
Volume 2014 (2014), Article ID 502414, 5 pages
http://dx.doi.org/10.1155/2014/502414
Research Article

Long Term Prospective Assessment of Living Kidney Donors: Single Center Experience

1Department of Nephrology, The Urology and Nephrology Center, Mansoura 35516, Egypt
2Department of Nephrology, Zagazig University, Zagazig 44519, Egypt
3Department of Radiology, Zagazig University, Zagazig 44519, Egypt
4Department of Urology, The Urology and Nephrology Center, Mansoura 35516, Egypt
5Department of Immunology, The Urology and Nephrology Center, Mansoura 35516, Egypt

Received 16 July 2013; Accepted 20 October 2013; Published 23 January 2014

Academic Editors: A. Meysamie and M. Z. Molnar

Copyright © 2014 Ayman Maher Nagib et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Virtually, all studies reporting the outcomes of living kidney donation beyond the first year from donation were retrospective. In this prospective study, the outcome of 81 consecutive living kidney donors was thoroughly evaluated. Clinical, laboratory, and radiological assessments were carried out at predonation (basal), 3, 6, 12, and 24 months after donation. The mean age at time of donation was 37.8 ± 9.8 years and the majority was females (75.3%). The mean BMI increased significantly after donation ( ). The mean serum creatinine levels (mg/dl) were 0.75 ± 0.14, 1.01 ± 0.22, 0.99 ± 0.21, 0.98 ± 0.20, and 0.94 ± 0.20 ( ). Likewise, the mean levels of measured creatinine clearance (mL/min) were 148.8 ± 35.7, 94.7 ± 26.6, 95.5 ± 24.6, 96.7 ± 20.2, and 101.6 ± 26.2 ( ). The mean 24 hours urinary protein excretion (gm/dL) were 0.09 ± 0.03, 0.19 ± 0.18, 0.16 ± 0.09, 0.18 ± 0.25, and 0.17 ± 0.12 ( ). There were significant increases in the means of the longitudinal and transverse diameters of the remaining kidney over time ( ). Out of 42 female donors, eleven female donors have got successful postdonation pregnancies. There were no reported surgical complications, either intra- or postoperative. Long-term follow-up is necessary for all living kidney donors through local institutional and world registries. This trial is registered with ClinicalTrials.gov NCT00813579.