Review Article

Molecular and Cellular Pathways of Immunoglobulin G Activity In Vivo

Figure 2

Effector pathway of IgG dependent B cell depletion and platelet phagocytosis. Upon binding of antibodies to B cells or to thrombocytes, resident monocytes characterized by low expression of Ly6C and high expression of FcγRIV are responsible for B cell and platelet removal.
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