Research Article
Mitochondrial DNA Haplogroups and Susceptibility to Prostate Cancer in a Colombian Population
Table 4
Association between prostate cancer risk and the population ancestry.
| Ancestry* | Control | Prostate cancer | Odds ratio (95% CI) | P value |
**Odds ratio (95% CI) | P value |
| Amerind | 119 (85%) | 135 (80.4%) | Reference | | Reference | | European | 18 (12.9%) | 22 (13.1%) | 1.08 (0.55–2.11) | 0.82 | 1.09 (0.43–2.78) | 0.85 | African | 3 (2.1%) | 11 (6.5%) | 3.23 (0.88–11.85) | 0.07 | 1.01 (0.18–5.61) | 0.99 | European | 18 (12.9%) | 22 (13.1%) | Reference | | Reference | | Amerind | 119 (85%) | 135 (80.4%) | 0.93 (0.48–1.81) | 0.52 | 0.91 (0.36–2.32) | 0.85 | African | 3 (2.1%) | 11 (6.5%) | 3 (0.73–12.41) | 0.12 | 0.35 (0.02–5.18) | 0.44 |
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Analysis of ancestry was assessed by the use of the major mtDNA haplogroups. Adjusted by age, history of cancer, and PSA.
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