Research Article

Mitochondrial DNA Haplogroups and Susceptibility to Prostate Cancer in a Colombian Population

Table 4

Association between prostate cancer risk and the population ancestry.

Ancestry*ControlProstate cancerOdds ratio (95% CI)P value **Odds ratio (95% CI)P value

Amerind119 (85%)135 (80.4%)ReferenceReference
European18 (12.9%)22 (13.1%)1.08 (0.55–2.11)0.821.09 (0.43–2.78)0.85
African3 (2.1%)11 (6.5%)3.23 (0.88–11.85)0.071.01 (0.18–5.61)0.99
European18 (12.9%)22 (13.1%)ReferenceReference
Amerind119 (85%)135 (80.4%)0.93 (0.48–1.81)0.520.91 (0.36–2.32)0.85
African3 (2.1%)11 (6.5%)3 (0.73–12.41)0.120.35 (0.02–5.18)0.44

Analysis of ancestry was assessed by the use of the major mtDNA haplogroups.
Adjusted by age, history of cancer, and PSA.