Hypertrophic Scar Formation on Application of Terpenoid Fraction of Tuberous Root of Mirabilis jalapa L. on Excision Wound Model in Wistar Albino Rats

Table 2

Effect of standard, MJE, and fractions on hydroxyproline, MDA, ascorbic acid content, and rate of wound contraction in excision wound model.

	Control	Standard	MJE	F1	F3
Hydroxyproline (mg/g of tissue)	5.88 ± 0.93	9.22 ± 1.41	7.12 ± 0.87	6.78 ± 0.38	7.307 ± 0.085
Malondialdehyde (µmol/g of tissue)	0.212 ± 0.074	0.1089 ± 0.094	0.1066 ± 0.044	0.0744 ± 0.054	0.1106 ± 0.099
Ascorbic acid (mg/g of tissue)	43.945 ± 4.71	58.375 ± 8.58	44.21 ± 1.12	32.14 ± 5.54	51.11 ± 4.82

Standard: silver sulfadiazine, MJE: hydromethanolic extract of M.  jalapa, F1: fraction 1, and F3: fraction 3, = 5; values are expressed as mean ± SD; versus control and one-way ANOVA analysis followed by Dunnett’s multiple comparison test was performed.