Table 1: Comparative statistics of demographic and basic clinical data and of scores of selected screening and diagnostic instruments.

AllESAS value of -test*

1004753
Gender50 M : 50 F26 M : 21 F24 M : 29 F
Hoehn and Yahr score (1–5) (1–2.5) (3–5)<0.01
Age (±SD); years (47–85) (47–76) (47–85)<0.01
Disease duration; years (0.5–19) (0.5–14) (0.5–19)<0.01
LEDD; mg (100–2000) (100–1500) (300–2000)<0.01
NMSQuest score (0–20) (0–18) (1–20)<0.01
NMSS total score (1–170) (1–82) (11–170)=0.02
PDQ-8 summary index (0–69) (0–53) (0–69)<0.01

Abbreviations: AS: advanced-stage Parkinson’s disease; ES: early-stage Parkinson’s disease; M: male; F: female; LEDD: levodopa equivalent daily dose.
*Comparison between early-stage and advanced-stage patients.
For explanation, see Section 2.2.
Values are displayed as arithmetic mean ± standard deviation (range).