Effect of
α-Lipoic Acid on Oxidative Stress in End-Stage Renal Disease Patients Receiving Intravenous Iron
Figure 2
Changes in serum F2-isoprostane (FIP) (a), lipid hydroperoxide (LHP) (b), and malondialdehyde (MDA) levels (mean ± SD) over time after intravenous iron infusion in control and intervention groups. In mixed-effect model with time as repeated measure a significant effect of α-lipoic acid (), time (), and α-lipoic-by-time interaction () was observed for changes in serum FIP [TOEP(2) matrix] and LHP level (TOEP matrix) and a significant effect of time () was observed for changes in serum MDA level [ANTE(1) matrix]. *Significant differences between groups, . The inset depicts the area under the curve (AUC) of oxidative stress marker levels FIP (), LHP (), and MDA () in control and intervention groups.
