Adding of Sitagliptin on Insulin Therapy Effectively and Safely Reduces a Hemoglobin A1c Level and Glucose Fluctuation in Japanese Patients with Type 2 Diabetes
Table 4
Relationship between HbA1c and each continuous variable.
Predictive variable
value
value
Age (years old)
0.064
N.S.
Duration of diabetes (years)
0.102
N.S.
Initial BMI
−0.039
N.S.
Initial HbA1c (%)
−0.577
<0.0001
Body weight (kg)
−0.196
0.005
Dose of insulin (U/day)
−0.008
N.S.
Fasting serum CPR (nmol/L)a
−0.222
0.026
Postprandial serum CPR (nmol/L)b
−0.08
N.S.
Within-day glucose variability (%)c
0.102
N.S.
Day-to-day glucose variability (%)c
0.107
N.S.
Abbreviations are shown in text. Pearson's correlation coefficient. = (value after 3 months) − (value before add-on of sitagliptin). , , and . N.S.: not significant.