Clinical Study

Adding of Sitagliptin on Insulin Therapy Effectively and Safely Reduces a Hemoglobin A1c Level and Glucose Fluctuation in Japanese Patients with Type 2 Diabetes

Table 4

Relationship between HbA1c and each continuous variable.

Predictive variable value value

Age (years old)0.064N.S.
Duration of diabetes (years)0.102N.S.
Initial BMI−0.039N.S.
Initial HbA1c (%) −0.577<0.0001
Body weight (kg)−0.1960.005
Dose of insulin (U/day)−0.008N.S.
Fasting serum CPR (nmol/L)a−0.2220.026
Postprandial serum CPR (nmol/L)b−0.08N.S.
Within-day glucose variability (%)c0.102N.S.
Day-to-day glucose variability (%)c0.107N.S.

Abbreviations are shown in text. Pearson's correlation coefficient.
= (value after 3 months) − (value before add-on of sitagliptin).
, , and . N.S.: not significant.