Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route

Table 2

Optimization of type and concentration of bioadhesive polymer.

Ingredients	Amount (mg/tablet)
	F1	F2	F3	F4	F5	F6	F7	F8	F9	C2
FSM	3.91	3.91	3.91	3.91	3.91	3.91	3.91	3.91	3.91	3.91
SSG	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70
NaCMC	0.43	1.70	4.25	—	—	—	—	—	—	—
HPMC K4M	—	—	—	0.43	1.70	4.25	—	—	—	—
Chitosan	—	—	—	—	—	—	0.43	1.70	4.25	—
SDL	53.49	52.60	50.81	53.49	52.60	50.81	53.49	52.60	50.81	53.788
MCC 102	22.92	22.54	21.78	22.92	22.54	21.78	22.92	22.54	21.78	23.052
CSD	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70	1.70
MS	0.85	0.85	0.85	0.85	0.85	0.85	0.85	0.85	0.85	0.85
Total weight (mg)	85.00	85.00	85.00	85.00	85.00	85.00	85.00	85.00	85.00	85.00