Table of Contents
International Scholarly Research Notices
Volume 2014, Article ID 689742, 4 pages
Clinical Study

Microbial Keratitis Profile at a University Hospital in Hong Kong

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, and Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital, Shatin, Hong Kong

Received 29 August 2014; Revised 5 October 2014; Accepted 22 October 2014; Published 11 November 2014

Academic Editor: Michelle Callegan

Copyright © 2014 Tracy H. T. Lai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate the recent trends in demographics, risk factors, and microbiological profiles of microbial keratitis at a university hospital in Hong Kong. Design. Retrospective review. Methods. The medical records of 51 patients admitted to the Prince of Wales Hospital for microbial keratitis from January 2010 to June 2012 were reviewed. Demographics, risk factors, clinical features, microbiological results, and treatment were recorded. Data was analyzed and compared to our historical sampled data collected 11 years ago. Results. The mean age of patients was 41.6 ± 20.3 years. Contact lens use was the major risk factor (45%), followed by injury (12%). The culture positive rate was 59%, of which 37% were Gram-positive organisms and 53% were Gram-negative organisms. Pseudomonas aeruginosa (50%) and coagulase-negative Staphylococcus (13%) were the most commonly isolated pathogens. No resistance to fluoroquinolones was identified. Conclusions. Our study showed that contact lens wear remained the major risk factor for microbial keratitis in Hong Kong and Pseudomonas aeruginosa remained the commonest bacterium isolated. This is comparable to our historical data and other studies conducted in East Asia.