Research Article
Metabolic Effects of Social Isolation in Adult C57BL/6 Mice
Figure 1
(a) Body weight at the start of the experiment (12 weeks) and following 2 months of differential housing conditions at 20 weeks was comparable between the groups ( for SI group, for group-housed control). (b) Serum biomarker profile after 2 months of social isolation showed robust increase in leptin level (–20 per group). (c) Interscapular BAT and WAT depots (from one side) were all increased by SI (SI, , control, ). (d) Adipocyte diameters were greater in WATi and WATr but not WATe in the SI mice (–5 mice per group, each mouse with over 10 measurements). Data shown are mean ± S.E.M. . .
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