Review Article

Corneal Biomechanical Properties in Different Ocular Conditions and New Measurement Techniques

Table 2

Summary of studies evaluating the influence of refractive surgery on biomechanical parameters.

AuthorSample (eyes)Outcomes
CH (mmHg)CRF (mmHg)

Pepose et al. (2007) [25]66 LASIKPrePostPrePost
 9.7 ± 1.8 8.0 ± 1.6 9.5 ± 1.9 6.7 ± 1.7

Ortiz et al. (2007) [4]65 LASIKPrePostPrePost
 10.44 ± 1.74 9.3 ± 1.9 10.07 ± 1.97 8.1 ± 1.8

Hamilton et al. (2008) [81]32 LASIK (flap with femtosecond):CH decreased 1.9 mmHg
33 LASIK (flap with microkeratome):CH decreased 2.2 mmHg
32 PRK:CH decreased 2.3 mmHg

Franco and Lira (2009) [30]63 control 10.8 ± 1.5310.6 ± 1.71
20 LASIK8.5 ± 1.227.7 ± 0.97

Qazi et al. (2009) [82]PrePostPrePost
15 LASEK  9.06 ± 1.56 7.16 ± 1.99 8.61 ± 1.76 5.95 ± 2.41
14 LASIK 10.00 ± 1.77 8.57 ± 2.25 9.87 ± 1.97 7.35 ± 2.49

Kamiya et al. (2009) [84] 36 LASIKPre:10.6Pre:10.0
Post:Post:
 1 week:8.6 1 week:7.3
 1 month:9.0 1 month:7.6
 3 months:9.0 3 months:7.8
 6 months:8.9 6 months:7.7

Kamiya et al. (2009) [83] PrePostPrePost
27 LASIK 10.8 8.6 10.3 7.7
31 PRK 10.8 9.2 10.3 8.4

Shah and Laiquzzaman (2009) [85]110 LASIKPre:Post:PrePost
 11.4 9.2 10.0 7.6

Chen et al. (2010) [86]60 LASIKPre:10.59 ± 1.02Pre:8.80 ± 1.45
Post:Post:
 1 day:8.16 ± 0.84 1 day:5.02 ± 1.16
 10 days:8.14 ± 0.77 10 days:4.96 ± 0.98
 1 month:8.33 ± 0.88 1 month:5.08 ± 1.31
 3 months:8.47 ± 0.78 3 months:5.26 ± 0.96

Ryan et al. (2011) [87]102 epi-LASIKPre:10.22Pre:10.01 ± 1.80
Post:Post:
 1 month:8.17 ± 1.25 1 month7.82 ± 1.68
 3 months:8.46 ± 1.44 3 months:8.03 ± 1.85
 6 months:8.63 ± 1.31 3 months:7.77 ± 1.50
 12 months:8.53 ± 1.49 3 months:7.80 ± 1.66

CH: corneal hysteresis; CRF: corneal resistance factor.