Table of Contents
International Scholarly Research Notices
Volume 2014, Article ID 751349, 7 pages
http://dx.doi.org/10.1155/2014/751349
Research Article

Effects of Traditional Chinese Medicine Qinbai Qingfei Concentrated Pellet on Cellular Infectivity of Mycoplasma pneumoniae

College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang 150030, China

Received 19 June 2014; Accepted 10 September 2014; Published 29 October 2014

Academic Editor: Ayman M. Noreddin

Copyright © 2014 Guo-Zheng Jiang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim. To study the effect and mechanism of traditional Chinese medicine Qinbai Qingfei concentrated pellet (QQCP) against Mycoplasma pneumoniae (MP). Methods. Rat airway smooth muscle (ASM) cells were used to examine the antimycoplasmal activity of QQCP via four drug-adding modes: pre- and postadding drugs, simultaneous-adding after drug and MP mixed, and simultaneous-adding drug and MP; taking roxithromycin dispersive tablets (RDT) as positive control, the cellular A570 values were determined by MTT method. Results. All of A570 values in QQCP group were significantly higher than those of the corresponding MP control group in four drug-adding modes; there was no significant difference in A570 values between the QQCP group and that of the positive control group , confirming that QQCP could significantly inhibit the infectivity of MP to ASM cells. Conclusion. QQCP had significant activity in preventing and treating MP infection, killing MP, and antiabsorption.