Table of Contents
ISRN Urology
Volume 2014, Article ID 759253, 5 pages
Research Article

Neutrophil-Lymphocyte Ratio in Small Renal Masses

1Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
2Columbia University Mailman School of Public Health, 722 W 168th Street, New York, NY 10032, USA
3University of California San Diego School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA

Received 7 February 2014; Accepted 27 February 2014; Published 12 March 2014

Academic Editors: T. Takayama, O. Tulunay, and W. Zhong

Copyright © 2014 Wassim M. Bazzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. To evaluate the association between preoperative neutrophil-lymphocyte ratio (NLR) and clinicopathologic characteristics in patients with small renal masses (SRM). Methods. Retrospective chart reviews of patients with renal masses ≤4 cm who underwent nephrectomy from January 2007 to July 2012 were conducted. Multivariable linear regression was used to examine the association between preoperative NLR and clinicopathologic variables. Results. In 1001 patients, we noted higher mean preoperative NLR in men ( versus in women, ) and Caucasians ( versus in African Americans, ) but no significant differences in patients with low (I-II) versus high (III-IV) American Society of Anesthesiologists (ASA) scores ( versus , ) or benign versus malignant pathology ( versus , ). Spearman correlation analysis ( ) showed preoperative NLR significantly correlated with age ( , ) and preoperative serum creatinine (Crea) [ , ]. On multivariable linear regression analysis older age, male gender, Caucasian race, and preoperative Crea were predictive of higher preoperative NLR, but ASA score and tumor pathology were not. Conclusions. In patients with SRM, we found no association between preoperative NLR and tumor pathology.