Preventative Effects of Caffeic Acid Phenyl Ester on Cadmium Intoxication Induced Hematological and Blood Coagulation Disturbances and Hepatorenal Damage in Rats

Table 2

Serum levels of liver and kidney function biomarkers.

Parameter	Units	Control group; (𝑛=10)	Cd group; (𝑛=15)	Cd + CAPE group; (𝑛=15)
AST	IU/L	109.00±12.17	571.33 ± 72.29*	163.00 ± 14.93^#
ALT	IU/L	49.17±3.27	136.07 ± 21.06*	73.33 ± 11.35^#
ALP	IU/L	206.33±20.79	274.33 ± 25.14*	211.33 ± 17.35^#
ALB	g/dL	4.33±0.59	2.86 ± 0.38*	4.01 ± 0.27^#
CRE	mg/dL	0.26±0.04	0.41 ± 0.34*	0.29 ± 0.01^#
BUN	mg/dL	47.36±9.12	63.65 ± 13.44*	49.22 ± 10.10^#

The values are presented as means ± SD. (Cd) cadmium, (CAPE) caffeic acid phenyl ester, (AST) aspartate aminotransferase, (ALT) alanine aminotransferase, (ALP) alkaline phosphatase (ALP), (ALB) albumin, (CRE) creatinine, and (BUN) blood urea nitrogen. *𝑃<0.05 versus control group; ^#𝑃<0.05 versus Cd group.