Comparison of Reverse Transcription Quantitative Real-Time PCR, Flow Cytometry, and Immunohistochemistry for Detection of Monoclonality in Lymphomas

Table 2

Monoclonal populations detected in lymphoma and lymphadenitis biopsies^a.

	RT-qPCR	FC	IHC
CLL	12/16	11/11	16/16
DLBL	14/20	10/13	19/20
FL	5/16	6/12	14/14
MCL	2/3	3/3	3/3
CLL/lymphoma total	33/55	30/39	52/53
LA	0/20	0/10	0/20

aNumber of samples with clonality proven/total number of samples is shown. CLL: chronic lymphocytic leukemia; DLBL: diffuse large B cell lymphoma; FL: follicular lymphoma; MCL: mantle cell lymphoma; LA: lymphadenitis (polyclonal control).