Factor VIII-Related Antigen Detects Phenotypic Change of Sinusoidal to Vascular Endothelium in Hepatic Fibrosis of Elderly Cadavers
Figure 5
Immunostaining of platelets for FVIIIRAg. (a) This image shows platelets (arrows) scattered in the lumen of sinusoids. (b) The platelets, measured 2–4 μm in diameter, are visibly larger than the FVIIIRAg immunoreactive granules associated with the sinusoidal endothelial cells (Figures 3-4 above). Furthermore, the platelets (arrows) characteristically display internal granular structures; this is due to the presence of organelles that are not observed in FVIIIRAg-positive granules in endothelial cells.
