Research Article

Factors Determining Survival and Retention among HIV-Infected Children and Adolescents in a Community Home-Based Care and a Facility-Based Family-Centred Approach in Kampala, Uganda: A Cohort Study

Table 1

Baseline characteristics of HIV-infected children and adolescents in a community home-based care model and a facility-based family-centred approach, Kampala, Uganda, 2003–2010.

CharacteristicsCommunity home-based care approach 
= 1,460
Facility-based family-centred approach 
= 163
Total
= 1,623
values
(%) (%) (%)

Age (months)
 <12 371 (25.4)54 (33.1)425 (26.2)0.097
 12–35 228 (15.6)21 (12.9)249 (15.3)
 36–59 173 (11.9)23 (14.1)196 (12.1)
 60+688 (47.1)65 (38.9)753 (46.4)
Gender
 Female746 (51.1)87 (53.4)833 (51.3)0.581
 Male714 (48.9)77 (46.6)790 (48.7)
Cd4 count and percent
 Median CD4 (IQR)393 (51–762)727 (442–1348)438 (78–824)<0.001
 Median CD4% (IQR)5.8 (0.1–16.9)17.0 (10.0–25.0)8.1 (0.2–18.1)<0.001
Level of immunosuppression by CD4
 Not significant273 (24.4)39 (25.0)312 (24.4)0.424
 Mild122 (10.8)21 (13.5)143 (11.1)
 Advanced131 (11.6)12 (7.7)143 (11.1)
 Severe605 (53.5)84 (53.8)689 (53.5)
On ART
 Yes441 (30.2)163 (100)604 (37.2)<0.001
 No1019 (69.8)0 (0.0)1019 (62.8)
Age at ART initiation (months)
 Median (IQR)91.0 (48.9–135.5)45.9 (6.5–85.0)78.6 (34.0–124.6)<0.001
WHO clinical staging
 I-II1258 (86.4)157 (96.9)1415 (87.5)<0.001
 III-IV198 (13.6)5 (3.1)203 (12.5)
Growth response weight-for-age
 ≤−2SD430 (37.4)24 (16.9)454 (35.2)<0.001
 >−2SD719 (62.6)118 (83.1)837 (64.8)
Height-for-age
 ≤−2SD508 (44.3)43 (30.3)551 (42.8) 0.001
 >−2SD639 (55.7)99 (69.7)738 (57.2)