Table of Contents
ISRN Microbiology
Volume 2014, Article ID 953417, 9 pages
http://dx.doi.org/10.1155/2014/953417
Research Article

Prevalence and Genetic Characterization of Carbapenem- and Polymyxin-Resistant Acinetobacter baumannii Isolated from a Tertiary Hospital in Terengganu, Malaysia

1Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Faculty of Agriculture, Biotechnology and Food Sciences, Universiti Sultan Zainal Abidin, 20400 Kuala Terengganu, Malaysia
3Faculty of Medicine and Health Sciences, Universiti Sultan Zainal Abidin, 20400 Kuala Terengganu, Malaysia
4Department of Pathology, Hospital Sultanah Nur Zahirah, 20400 Kuala Terengganu, Malaysia

Received 5 December 2013; Accepted 9 February 2014; Published 19 March 2014

Academic Editors: B. Ayo, K. Leung, and C. Pazzani

Copyright © 2014 Soo-Sum Lean et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [23 citations]

The following is the list of published articles that have cited the current article.

  • Soo-Sum Lean, Chew Chieng Yeo, Zarizal Suhaili, and Kwai-Lin Thong, “Whole-genome analysis of an extensively drug-resistant clinical isolate of Acinetobacter baumannii AC12: insights into the mechanisms of resistance of an ST195 clone from Malaysia,” International Journal of Antimicrobial Agents, 2014. View at Publisher · View at Google Scholar
  • Abiola O. Olaitan, Serge Morand, and Jean-Marc Rolain, “Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria,” Frontiers in Microbiology, vol. 5, 2014. View at Publisher · View at Google Scholar
  • Dabet Rynga, Malini Shariff, and Monorama Deb, “Phenotypic and molecular characterization of clinical isolates of Acinetobacter baumannii isolated from Delhi, India,” Annals of Clinical Microbiology and Antimicrobials, vol. 14, no. 1, 2015. View at Publisher · View at Google Scholar
  • Wei Jia, Caiyun Li, Haiyun Zhang, Gang Li, Xiaoming Liu, and Jun Wei, “Prevalence of Genes of OXA-23 Carbapenemase and AdeABC Efflux Pump Associated with Multidrug Resistance of Acinetobacter baumannii Isolates in the ICU of a Comprehensive Hospital of Northwestern China,” International Journal of Environmental Research and Public Health, vol. 12, no. 8, pp. 10079–10092, 2015. View at Publisher · View at Google Scholar
  • Abed Zahedi Bialvaei, and Hossein Samadi Kafil, “Colistin, mechanisms and prevalence of resistance,” Current Medical Research & Opinion, pp. 1–15, 2015. View at Publisher · View at Google Scholar
  • Thien B Tran, Soon-Ee Cheah, Heidi H Yu, Phillip J Bergen, Roger L Nation, Darren J Creek, Anthony Purcell, Alan Forrest, Yohei Doi, Jiangning Song, Tony Velkov, and Jian Li, “Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii,” The Journal of Antibiotics, 2015. View at Publisher · View at Google Scholar
  • Sofiane Bakour, Abiola Olumuyiwa Olaitan, Houria Ammari, Abdelaziz Touati, Souad Saoudi, Kenza Saoudi, and Jean-Marc Rolain, “ Emergence of Colistin- and Carbapenem-Resistant Acinetobacter baumannii ST2 Clinical Isolate in Algeria: First Case Report ,” Microbial Drug Resistance, pp. 150114112337003, 2015. View at Publisher · View at Google Scholar
  • Md Mostafizur Rahman, Shirin Biglari, Ramli Ramliza, and Hanafiah Alfizah, “Molecular characterization of carbapenemase and cephalosporinase genes among clinical isolates of Acinetobacter baumannii in a tertiary medical centre in Malaysia,” Journal of Medical Microbiology, vol. 64, no. 1, pp. 53–58, 2015. View at Publisher · View at Google Scholar
  • Amreeta Dhanoa, Ganeswrie Rajasekaram, Soo Sum Lean, Yuet Meng Cheong, and Kwai Lin Thong, “ Endemicity of Acinetobacter calcoaceticus-baumannii Complex in an Intensive Care Unit in Malaysia ,” Journal of Pathogens, vol. 2015, pp. 1–8, 2015. View at Publisher · View at Google Scholar
  • Maryam Pourhajibagher, Ebrahim Boluki, Nasim Chiniforush, Babak Pourakbari, Zahra Farshadzadeh, R. Ghorbanzadeh, Masoud Aziemzadeh, and Abbas Bahador, “Modulation of virulence in Acinetobacter baumannii cells surviving photodynamic treatment with toluidine blue,” Photodiagnosis and Photodynamic Therapy, vol. 15, pp. 202–212, 2016. View at Publisher · View at Google Scholar
  • Nuntra Suwantarat, and Karen C. Carroll, “Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast Asia,” Antimicrobial Resistance And Infection Control, vol. 5, 2016. View at Publisher · View at Google Scholar
  • Shirin Biglari, Alfizah Hanafiah, Shaliawani Mohd Puzi, Ramliza Ramli, Mostafizur Rahman, and Bruno Silvester Lopes, “ Antimicrobial Resistance Mechanisms and Genetic Diversity of Multidrug-Resistant Acinetobacter baumannii Isolated from a Teaching Hospital in Malaysia ,” Microbial Drug Resistance, 2016. View at Publisher · View at Google Scholar
  • Soo-Sum Lean, Chew Chieng Yeo, Zarizal Suhaili, and Kwai-Lin Thong, “Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism,” Frontiers in Microbiology, vol. 6, 2016. View at Publisher · View at Google Scholar
  • Soo Sum Lean, and Chew Chieng Yeo, “Small, Enigmatic Plasmids of the Nosocomial Pathogen, Acinetobacter baumannii: Good, Bad, Who Knows?,” Frontiers in Microbiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Katy Jeannot, Arnaud Bolard, and Patrick Plésiat, “Resistance to polymyxins in Gram-negative organisms,” International Journal of Antimicrobial Agents, 2017. View at Publisher · View at Google Scholar
  • Farahiyah Mohd. Rani, Nor Iza A. Rahman, Salwani Ismail, Ahmed Ghazi Alattraqchi, David W. Cleary, Stuart C. Clarke, and Chew Chieng Yeo, “Acinetobacter spp. Infections in Malaysia: A Review of Antimicrobial Resistance Trends, Mechanisms and Epidemiology,” Frontiers in Microbiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Gabriela Da Silva, and Sara Domingues, “Interplay between Colistin Resistance, Virulence and Fitness in Acinetobacter baumannii,” Antibiotics, vol. 6, no. 4, pp. 28, 2017. View at Publisher · View at Google Scholar
  • Farahiyah Mohd Rani, Nor Iza A. Rahman, Salwani Ismail, Fatimah Haslina Abdullah, Norlela Othman, Ahmed Ghazi Alattraqchi, David W. Cleary, Stuart C. Clarke, and Chew Chieng Yeo, “Prevalence and antimicrobial susceptibilities of Acinetobacter baumannii and non-baumannii Acinetobacters from Terengganu, Malaysia and their carriage of carbapenemase genes,” Journal of Medical Microbiology, 2018. View at Publisher · View at Google Scholar
  • Michelle Lowe, Marthie M. Ehlers, Farzana Ismail, Gisele Peirano, Piet J. Becker, Johann D. D. Pitout, and Marleen M. Kock, “Acinetobacter baumannii: Epidemiological and Beta-Lactamase Data From Two Tertiary Academic Hospitals in Tshwane, South Africa,” Frontiers in Microbiology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Deepti P. Karumathil, Meera Surendran Nair, James Gaffney, Anup Kollanoor-Johny, and Kumar Venkitanarayanan, “Trans-Cinnamaldehyde and Eugenol Increase Acinetobacter baumannii Sensitivity to Beta-Lactam Antibiotics,” Frontiers in Microbiology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • William Gustavo Lima, Mara Cristina Alves, Waleska Stephanie Cruz, and Magna Cristina Paiva, “Chromosomally encoded and plasmid-mediated polymyxins resistance in Acinetobacter baumannii: a huge public health threat,” European Journal of Clinical Microbiology & Infectious Diseases, 2018. View at Publisher · View at Google Scholar
  • Yamuna Devi Bakthavatchalam, Agila Kumari Pragasam, Indranil Biswas, and Balaji Veeraraghavan, “Polymyxin susceptibility testing, interpretative breakpoints and resistance mechanisms: An update,” Journal of Global Antimicrobial Resistance, vol. 12, pp. 124–136, 2018. View at Publisher · View at Google Scholar
  • Amani T. Abdulzahra, Mahmoud A.F. Khalil, and Walid F. Elkhatib, “First report of colistin resistance among carbapenem-resistant Acinetobacter baumannii isolates recovered from hospitalized patients in Egypt,” New Microbes and New Infections, vol. 26, pp. 53–58, 2018. View at Publisher · View at Google Scholar