Plasma Aminothiol Profile and Some of Its Determinants in Apparently Healthy Azorean Subjects

Table 3

Conventional risk factors in subjects with an aPAP, split by 3 subgroups.

Parameters	aPAP
	aPAP-1 (129)	aPAP-2 (62)	aPAP-3 (56)
Sex, male (%)	22	63*	66^†
Age (years)	44 ± 9	39 ± 10*	41 ± 8
Smoking (%)	16	23	37^†
Blood pressure (mmHg)
Systolic BP	134 ± 25	128 ± 20	131 ± 19
Diastolic BP	81 ± 15	79 ± 12	81 ± 13
Hypertension (%)	47	42	55
BMI (Kg/m^2)
Overweight (%)	34	53*	46
Obese (%)	43	24*	30
Serum lipids (mg/dL)
Triglycerides	123±63	127±75	129±63
Total cholesterol	211±35	208±41	206±37
HDL cholesterol	61±15	56±15	56±16
LDL cholesterol	128±33	133±40	128±36
Hyperlipidemia (%)	71	69	61
Serum GGT activity (U/L)	33±34	26±15	59 ± 57^†‡
Plasma vitamins
Folate (ng/mL)	9±4	7 ± 2*	7 ± 2^†
Vitamin B12 (pg/mL)	604±360	553±226	494±280
Vitamin B6 (nmol/L)	56±33	53±27	47±19

aPAP-1: only low GSH; aPAP-2: at least one aminothiol (Hcy, Cys, or Cys-Gly) elevated and normal GSH; aPAP-3: at least one aminothiol (Hcy, Cys, or Cys-Gly) elevated and low GSH; NS: not significant. Values are presented as mean ± SD, except otherwise indicated. Figures in parenthesis are the number of subjects (𝑛).
∗P < 0.05 when comparing aPAP-1 and aPAP-2 groups.
†P < 0.05 when comparing aPAP-1 and aPAP-3 groups.
‡P < 0.05 when comparing aPAP-2 and aPAP-3 groups.