Research Article

Examining Provincial HPV Vaccination Schemes in Canada: Should We Standardise the Grade of Vaccination or the Number of Doses?

Table 2

List of parameters and state variables.

ParameterDescriptionRangeSample valueReference

Unvaccinated children in grade (State variable)
Unvaccinated adult women(State variable)
Vaccinated children in grade (State variable)
Vaccinated adult women(State variable)
Uninfected adult women(State variable)
Infected adult women(State variable)
Uninfected men(State variable)
Infected men(State variable)
, Birth rate for women, men 50–100 people 100[4]
Mortality rate for children1/50–1/90 year−11/901/avg. time in compartment
Leaving rate for adults1/12–1/8 year−11/101/avg. time in compartment
Vaccine efficacy in female children93.3–99.8% 2 doses 0.97[3]
93.3–99.8% 3 doses0.99[3]
Vaccine efficacy in adult women50.2–96.3% 2 doses 0.809[3, 5, 2124]
71.1–87.7% 3 doses 0.841[3, 5, 2124]
, where Proportion of children vaccinated within the corresponding grade0–100% [16, 17, 19, 20]
Proportion of previously unvaccinated adult women vaccinated0–100% [16, 17, 19, 20]
Transmission of infection of a woman by an infected man0.01–2 year−1 0.77 [2]
Transmission of infection of a man by an infected woman0.01–2 year−10.77[2]
Proportion of infected girls at age 15 unvaccinated, vaccinated0–30%10%[25]
Probability of protection against all targeted types0.3–10.44[23]
Recovery rate for unvaccinated women, vaccinated women, men1/2–4/3 year−12/3[26, 27]
Attenuation constant0–0.3 year−1[4]
Maximal possible rate of adult vaccination0–0.20.1[4]
Rate at which unvaccinated women are vaccinated[4]
Waning rate0.2–1 year−1 2 doses 0.5[28]
0.1–0.5 year−1 3 doses0.333[28]