Oral Metformin Treatment Counteracts Adipoinsular Axis Dysfunction in Hypothalamic Obese Rats

Figure 1

Animal growing curves drawn throughout ages 60 to 90 days (a) and body weight values recorded at age 90 days (b) in different groups of experimental animals. Daily food intake registered between 60 and 90 days of age (c) and the 30-day average of daily food intake and body weight values recorded at age 90 days (d) in CTR, MSG, and MSG + metformin (MSG + MF) rats. Values means ± SEM ( rats per group). or less versus CTR values.

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