Review Article
Systematic Review: Adjuvant Chemotherapy for Locally Advanced Rectal Cancer with respect to Stage of Disease
Table 2
Baseline characteristics of rectal cancer patients in included studies.
| | Number of patients |
Age |
Male (%) | Stage II rectal cancer | Stage III rectal cancer | Previous treatment | | Total | Chemotherapy (%) | Control (%) | Chemotherapy (%) | Control (%) | Chemotherapy (%) | Control (%) | Chemotherapy | Radiotherapy |
| Glimelius et al. 2005 [11] | 691 | 339 (49) | 352 (51) | 64 versus 66 | NR | 160 (23) | 163 (24) | 179 (26) | 189 (27) | No | No |
| CCCSGJ 1995 [12] | 761 | 516 (68) | 245 (32) | 57 versus 60 | NR | 229 (30) | 120 (16) | 287 (38) | 125 (16) | No | No |
| Fisher et al. 1988 [13] | 371 | 187 (50) | 184 (50) | 61 versus 61 | 240 (64) | 72 (19) | 67 (18) | 115 (31) | 117 (32) | No | No |
| Kato et al. 2002 [14] | 129 | 66 (51) | 63 (49) | 60.2 versus 61.4 | NR | 26 (20) | 26 (20) | 40 (31) | 37 (29) | No | No |
| Kodaira et al. 1998 [15] | 670 | 331 (49) | 339 (51) | NR | NR | 154 (23) | 162 (25) | 177 (26) | 177 (26) | No | No |
| Hamaguchi et al. 2011 [16] | 274 | 139 (51) | 135 (49) | 59 versus 58 | 165 (60) | NR | NR | 139 (51) | 135 (49) | No | No |
| QUASAR 2007 [17] | 817 | 410 (50) | 407 (50) | NR | NR | 410 (50) | 407 (50) | NR | NR | No | No |
| Sakamoto et al. 2007 [18] | 1814 | 966 (53) | 848 (47) | NR | NR | 377 (21) | 316 (17) | 589 (33) | 532 (29) | No | No |
| Total | 5527 | 2954 (53) | 2573 (47) | — | — | 1428 (26) | 1261 (23) | 1526 (27) | 1312 (24) | — | — |
|
|
NR: not reported.
|