Systematic Review: Adjuvant Chemotherapy for Locally Advanced Rectal Cancer with respect to Stage of Disease

Table 3

Disease-free survival reported by included studies.

Study	DFS
	Stage II				Stage III
	Control	Intervention		Statistical significance	Control	Intervention		Statistical significance
CCCSGJ 1995 [12]	62.7%	Arm 1; 85.4%; = S	Arm 2; 78.8%; = S		39.3%	Arm 1; 53.1%; = NS	Arm 2; 62.9%; = S
Fisher et al.; 1988 [13]	39%	61%		S	25%	29%		S
Kato et al.; 2002 [14]	50.0%	87.8%		S	37.1%	65.0%		S
Kodaira et al.; 1998 [15]	67.5%	77.3%		NS	40.7%	54.5%		S
Hamaguchi et al. 2011 [16]	Not Reported	Not Reported			56.3%	68.9%		S
QUASAR 2007 [17]	76.7%	82.9%		S	Not Reported	Not Reported
Sakamoto et al. 2007 [18]	66.4%	77.1%		S	46.5%	55.0%		S

DFS: disease-free survival, S: significant, and NS: not significant.