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International Scholarly Research Notices
Volume 2017 (2017), Article ID 4781279, 4 pages
Research Article

The Severity of Retinopathy in the Extremely Premature Infants

1Department of Ophthalmology, Konstantopouleio General Hospital, Athens, Greece
2Department of Obstetrics and Gynecology, Venizeleio General Hospital of Heraklion, Crete, Greece
3Neonatology Department, Venizeleio General Hospital of Heraklion, Crete, Greece
4Department of Anesthesiology, University Hospital of Heraklion, Crete, Greece

Correspondence should be addressed to Alexandra Trivli

Received 10 August 2017; Accepted 24 September 2017; Published 18 October 2017

Academic Editor: Jing Chen

Copyright © 2017 Alexandra Trivli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. We aimed to investigate the incidence and the severity of retinopathy of extremely premature infants and to evaluate the risk factors and outcome of the cases. Materials and Methods. Out of 200 premature births, we retrospectively reviewed 9 cases that developed ROP. We excluded cases where ROP developed in newborns > 30 weeks of gestational age and cases where medical notes were unavailable or incomplete. Topical drops of cyclopentolate 1% and phenylephrine 5% were instilled and fundoscopy was performed using a direct ophthalmoscope. Results. The incidence of ROP was 4.5% in the 9-year period. The infants were divided into two groups. Group 1 included premature infants ≤27 weeks of age and Group 2 included those >27 weeks but ≤ 30 weeks of age. We found that the infants of Group 1 showed advanced stages of ROP in comparison to Group 2. Out of 18 eyes, 11 eyes had stage 3 ROP and they were all found in Group 1 (100% of cases). Conclusion. The severity of ROP was associated with earlier gestational age, lower birth weight, and oxygen supplementation. Constant cooperation between physicians and nursing staff is necessary to avoid undetected cases and further prevent ROP related blindness.