Research Article
The Ethanolic Stem-Bark Extract of Antrocaryon micraster Inhibits Carrageenan-Induced Pleurisy and Pedal Oedema in Murine Models of Inflammation
Figure 3
Effect of Antrocaryon micraster extract on histopathological changes in lung tissues of rats with carrageenan-induced pleurisy. Sprague Dawley rats (200–250 g) were untreated or treated with either normal saline (5 ml/kg), diclofenac (10 mg/kg), or AME (30–300 mg/kg) p.o. Pleurisy was induced as described in Methods. Lung tissues were fixed in formalin (10%), processed, and stained with H&E. Representative photomicrographs of the histology of lung tissues are shown. Naïve control (a), vehicle-treated control (b), diclofenac 10 mg/kg (c), AME 30 mg/kg (d), AME 100 mg/kg (e), and AME 300 mg/kg (f).
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