In this postgenomic era, a huge volume of information derived from expressed sequence tags (ESTs) has been constructed for functional description of gene expression profiles. Comparative studies have become more and more important to researchers of biology. In order to facilitate these comparative studies, we have constructed a user-friendly EST annotation pipeline with comparison tools on an integrated EST service website, Bio301. Bio301 includes regular EST preprocessing, BLAST similarity search, gene ontology (GO) annotation, statistics reporting, a graphical GO browsing interface, and microarray probe selection tools. In addition, Bio301 is equipped with statistical library comparison functions using multiple EST libraries based on GO annotations for mining meaningful biological information.

Yen-Chen Chen

Yun-Ching Chen

Wen-Dar Lin

Chung-Der Hsiao

Hung-Wen Chiu

Jan-Ming Ho

Bio301: A Web-Based EST Annotation Pipeline That Facilitates Functional Comparison Studies

Automotive Engineering

Atmospheric Sciences

Astronomy and Astrophysics

Applied Mathematics

Anesthesiology

Anatomy

Analytical Chemistry

Allergy

Algebra

Agronomy

Aerospace Engineering

Addiction

Botany

Biotechnology

Biophysics

Biomedical Engineering

Biomaterials

Biomarkers

Bioinformatics

Biochemistry

Critical Care

Condensed Matter Physics

Computer Science

Computer Engineering

Computational Mathematics

Computational Biology

Civil Engineering

Chemical Engineering

Cell Biology

Cardiology

Discrete Mathematics

Developmental Biology

Dermatology

Dentistry

Evolutionary Biology

Epidemiology

Environmental Chemistry

Energy

Endocrinology

Emergency Medicine

Electronics

Electrical Engineering

Ecology

Family Medicine

Geriatrics

Geophysics

Geometry

Geology

Genomics

Genetics

Gastroenterology

High Energy Physics

Hepatology

Hematology

Inorganic Chemistry

Infectious Diseases

Industrial Engineering

Immunology

Molecular Biology

Microbiology

Meteorology

Mechanical Engineering

Mathematical Physics

Mathematical Analysis

Materials Science

Nutrition

Nursing

Neuroscience

Neurology

Nephrology

Nanotechnology

Oxidative Medicine

Otolaryngology

Orthopedics

Organic Chemistry

Optics

Ophthalmology

Operations Research

Oncology

Oceanography

Obstetrics and Gynecology

Obesity

Pulmonology

Public Health

Psychiatry

Probability and Statistics

Physiology

Physical Chemistry

Pharmacology

Pharmaceutics

Pediatrics

Pathology

Parasitology

Rheumatology

Rehabilitation

Radiology

Surgery

Structural Biology

Soil Science

Toxicology

Tissue Engineering

Thermodynamics

Urology

Virology

Veterinary Science

Vascular Medicine

Zoology

About this journal

Journal profile

Meet the editorial board

Editor spotlight

Find out more

This journal's articles appear in a wide range of abstracting and indexing databases, and are covered by numerous other services that aid discovery and access. Find out more about where and how the content of this journal is available.

International Scholarly Research Notices

Table of Contents

Table of Contents

Bio301: A Web-Based EST Annotation Pipeline That Facilitates Functional Comparison Studies