Figure 2: Activation of specific brain areas by c-fos expression. Representative brain coronal sections of nonallergic (nonsensitized) and allergic (OVA-sensitized) mice after (oral or nasal) challenge with OVA. Fos staining in neurons of (a) the paraventricular nucleus of the hypothalamus (PVN), (b) nucleus of the tract solitary (NTS), and (c) central nucleus of the amygdala (CeA). Adapted from Basso et al. 2004 [36] and Costa-Pinto et al. [47].