Table of Contents
Journal of Allergy
Volume 2011, Article ID 267542, 7 pages
Clinical Study

Exercise-Induced Bronchoconstriction and Exercise-Induced Respiratory Symptoms in Nurses

1Department of Cardiorespiratory Functional Diagnostics, Institute for Occupational Health of R. Macedonia—WHO Collaborating Center and GA2LEN Collaborating Center, II Makedonska Brigada 43, 1000 Skopje, Macedonia
2Institute for Epidemiology and Biostatistics, 1000 Skopje, Macedonia

Received 20 December 2010; Accepted 28 February 2011

Academic Editor: Donald H. Beezhold

Copyright © 2011 Jordan Minov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In order to assess prevalence and characteristics of exercise-induced respiratory symptoms (EIRSs) and exercise-induced bronchoconstriction (EIB) in health care workers, we performed a cross-sectional study including 48 female nurses from primary care settings and an equal number of female office workers studied as a control group. The evaluation of examined groups included completion of a questionnaire, skin prick tests to common inhalant allergens, spirometry, and exercise and histamine challenge. We found a similar prevalence of EIRSs and EIB in both groups. EIB was closely related to asthma, atopy, family history of asthma, and positive histamine challenge in either group, while the association between EIB and daily smoking in nurses was of borderline statistical significance. Bronchial reaction to exercise was significantly higher in nurses than in controls with EIB. With the exception of exercise induced wheezing, EIRSs were weakly associated with EIB in both groups with a large proportion of false positive results.