Review Article

Sphingolipids: A Potential Molecular Approach to Treat Allergic Inflammation

Table 2

Synthetic inhibitors of SK and S1P receptors.

CompoundInhibitory target(s)StructureRef.

SKI-IISK-1
SK-2
154174.table.002a[75]

DMSSK-1
SK-2
154174.table.002b[76]

FTY720SK-1
S1P1, 3, 4, 5
154174.table.002c[77]

CB5468139SK-1154174.table.002d[78]

PF543SK-1154174.table.002e[79]

SK1-ISK-1154174.table.002f[80]

Compound 1aSK-1154174.table.002g[81]

ABC294640SK-2154174.table.002h[82]

SLR080811SK-2154174.table.002i[83]

W146S1P1154174.table.002j[84]

VPC44116S1P1 & 3154174.table.002k[85]

VPC23019S1P1 & 3154174.table.002l[86]

JTE013S1P2154174.table.002m[87]

CAY10444S1P3154174.table.002n[88]