Journal of Allergy

Research Article

Combined Beta-Agonists and Corticosteroids Do Not Inhibit Extracellular Matrix Protein Production In Vitro

Table 3

Effect of combined corticosteroids and LABAs on basal and TGF -stimulated IL6 release.
AsthmaticAloneNonasthmaticAlone
—F 10−10 MF 10−8 M—F 10−10 MF 10−8 M
Alone— —
B 10−10 M B 10−10 M
B 10−8 M B 10−8 M
TGF stimulatedTGF stimulated
—F 10-10 MF 10-8 M—F 10−10 MF 10−8 M
TGFβ stimulated— —
B 10−10 M B 10−10 M
B 10−8 M B 10−8 M
F: formoterol, B: budesonide.
Data are expressed as mean ±SEM % 0.1% ITS for drugs alone and % TGFβ for TGFβ-stimulated samples. asthmatic and 8 nonasthmatic.