Journal of Allergy / 2012 / Article / Tab 2

Research Article

The IL1B-511 Polymorphism (rs16944 AA Genotype) Is Increased in Aspirin-Exacerbated Respiratory Disease in Mexican Population

Table 2

Summary of clinical characteristics of AERD, ATA, and HCS.

AERDATAHCS

Subjects78135134
Gender (male/female)31/4749/8679/55
Mean age (years, SD)42.0 (14.4)36.7 (17)24 (8.9)
Premethacholine challenge FEV1 (%)99.6 (17.3)101.4 (12.9)98.2 (13.3)
Postmethacholine challenge FEV1 (%)75.1 (13.8)76.9 (14.4)95.4 (11.6)
Pre-L-ASA challenge nasal flow (mL/sec)640.75 (162.2)689 (178.2)670.2 (167.5)
Post-L-ASA challenge nasal flow (mL/sec)488 (142.8)658.5 (186.3)682.4 (165.7)

AERD: Aspirin-exacerbated respiratory disease, ATA: Aspirin-tolerant asthma, HCS: Healthy control subjects, SD: Standard deviation, FEV1: Forced expiratory volume in one second, L-ASA: Lysine aspirin.

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