Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children: Safety and Tolerance

Table 2

Classification of allergic reactions after HL Mueller, modified.

	Reaction
Large local reaction	Swelling at site of sting with diameter >10 cm, lasting >24 h
Grade I	Generalized urticaria, itching, malaise, anxiety
Grade II	Any of the above, plus two or more of the following: angiooedema (grade II also if alone), constriction in chest, nausea, vomiting, diarrhoea, abdominal pain, dizziness
Grade III	Any of the above, plus two or more of the following: dyspnoea, wheezing, stridor (any of these alone are grade III), dysphagia, dysarthria, hoarseness, weakness, confusion, fear of death
Grade IV	Any of the above, plus two or more of the following: drop of blood pressure, collapse, loss of consciousness, incontinence (urine, stool), cyanosis