Table of Contents
Journal of Allergy
Volume 2012, Article ID 819176, 13 pages
http://dx.doi.org/10.1155/2012/819176
Research Article

Immunolocalization of NLRP3 Inflammasome in Normal Murine Airway Epithelium and Changes following Induction of Ovalbumin-Induced Airway Inflammation

1Centre for Inflammatory Disease Research (CIDR), The Basil Hetzel Institute for Translational Health Research, Woodville South, SA 5011, Australia
2Stroke Research Programme and Neurology Department, University of Adelaide School of Medicine, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia
3School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, SA 5005, Australia
4Department of Surgery–Otorhinolaryngology Head and Neck Surgery, University of Adelaide, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia
5Rheumatology Department, The Queen Elizabeth Hospital, Woodville Road, Woodville South, SA 5011, Australia
6Discipline of Medicine 5B, University of Adelaide, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia

Received 14 June 2011; Revised 15 August 2011; Accepted 4 December 2011

Academic Editor: Darryl A. Knight

Copyright © 2012 Hai B. Tran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [23 citations]

The following is the list of published articles that have cited the current article.

  • Jeremy A. Hirota, “Human airway epithelial cell innate immunity: relevance to asthma,” Current Opinion in Immunology, vol. 24, no. 6, pp. 740–746, 2012. View at Publisher · View at Google Scholar
  • Johannes Rotta Detto Loria, Kristina Rohmann, Daniel Droemann, Peter Kujath, Jan Rupp, Torsten Goldmann, and Klaus Dalhoff, “Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1 beta - A Possible Pathway of Exacerbations in COPD,” Plos One, vol. 8, no. 6, 2013. View at Publisher · View at Google Scholar
  • Alice Prince, “Epithelial Uptake of Flagella Initiates Proinflammatory Signaling,” Plos One, vol. 8, no. 3, 2013. View at Publisher · View at Google Scholar
  • Camille Jardeleza, Dijana Miljkovic, Leonie Baker, Samuel Boase, Neil Cheng-Wen Tan, Simon A. Koblar, Peter Zalewski, Maureen Rischmueller, Susan Lester, Amanda Drilling, Damien Jones, Lor Wai Tan, Peter-John Wormald, and Sarah Vreugde, “Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis,” Rhinology, vol. 51, no. 4, pp. 315–322, 2013. View at Publisher · View at Google Scholar
  • Dominic De Nardo, Christine M. De Nardo, and Eicke Latz, “New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease,” The American Journal of Pathology, 2013. View at Publisher · View at Google Scholar
  • Janet Grant, Eugene Roscioli, Chiara Murgia, Rhys Hamon, Susan Lester, and Peter Zalewski, “Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways,” Biometals, vol. 26, no. 2, pp. 205–227, 2013. View at Publisher · View at Google Scholar
  • Suffwan Eltom, Maria G. Belvisi, Liang Yew-Booth, Bilel Dekkak, Sarah A. Maher, Eric D. Dubuis, Victoria Jones, Kate A. Fitzgerald, and Mark A. Birrell, “TLR4 activation induces IL-1 beta release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung,” Respiratory Research, vol. 15, 2014. View at Publisher · View at Google Scholar
  • Na-Ra Han, Ji-Hyun Go, Hyung-Min Kim, and Hyun-Ja Jeong, “Hyperoside Regulates the Level of Thymic Stromal Lymphopoietin through Intracellular Calcium Signalling,” Phytotherapy Research, vol. 28, no. 7, pp. 1077–1081, 2014. View at Publisher · View at Google Scholar
  • Keiki Ogino, Ran Zhang, Hidekazu Takahashi, Kei Takemoto, Masayuki Kubo, Ikuo Murakami, Da-Hong Wang, and Yoshihisa Fujikura, “Allergic Airway Inflammation by Nasal Inoculation of Particulate Matter (PM2.5) in NC/Nga Mice,” Plos One, vol. 9, no. 3, 2014. View at Publisher · View at Google Scholar
  • H. Im, “The NLRP3 inflammasome: role in airway inflammation,” Clinical and Experimental Allergy, vol. 44, no. 2, pp. 160–172, 2014. View at Publisher · View at Google Scholar
  • Rhys Hamon, Claire C. Homan, Hai B. Tran, Violet R. Mukaro, Susan E. Lester, Eugene Roscioli, Mariea D. Bosco, Chiara M. Murgia, Margaret Leigh Ackland, Hubertus P. Jersmann, Carol Lang, Peter D. Zalewski, and Sandra J. Hodge, “Zinc and Zinc Transporters in Macrophages and Their Roles in Efferocytosis in COPD,” Plos One, vol. 9, no. 10, 2014. View at Publisher · View at Google Scholar
  • Fadila Telarevic Cero, Vigdis Hillestad, Ivar Sjaastad, Arne Yndestad, PaL Aukrust, Trine Ranheim, Ida Gjervold Lunde, Maria Belland Olsen, Egil Lien, Lili Zhang, Solveig Bjaerum Haugstad, Else Marit Loberg, Geir Christensen, Karl-Otto Larsen, and Ole Henning Skjonsberg, “Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice,” American Journal Of Physiology-Lung Cellular And Molecular Physiology, vol. 309, no. 4, pp. L378–L387, 2015. View at Publisher · View at Google Scholar
  • Paul M. Peeters, Emiel F. Wouters, and Niki L. Reynaert, “Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed,” Journal of Immunology Research, vol. 2015, pp. 1–15, 2015. View at Publisher · View at Google Scholar
  • Luis Rafael Silva, and Denis Girard, “Human eosinophils are direct targets to nanoparticles: Zinc oxide nanoparticles (ZnO) delay apoptosis and increase the production of the pro-inflammatory cytokines IL-1β and IL-8,” Toxicology Letters, 2016. View at Publisher · View at Google Scholar
  • Sivakumar Periasamy, Hongnga T Le, Ellen B Duffy, Heather Chin, and Jonathan A Harton, “Inflammasome-Independent NLRP3 Restriction of a Protective Early Neutrophil Response to Pulmonary Tularemia.,” PLoS pathogens, vol. 12, no. 12, 2016. View at Publisher · View at Google Scholar
  • Pervinder Sagoo, Zacarias Garcia, Beatrice Breart, Fabrice Lemaître, David Michonneau, Matthew L Albert, Yves Levy, and Philippe Bousso, “In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity.,” Nature medicine, vol. 22, no. 1, pp. 64–71, 2016. View at Publisher · View at Google Scholar
  • Hiroshi Nakanishi, Yoshiyuki Kawashima, Kiyoto Kurima, Jae Jin Chae, Astin M. Ross, Gineth Pinto-Patarroyo, Seema K. Patel, Julie A. Muskett, Jessica S. Ratay, Parna Chattaraj, Yong Hwan Park, Sriharsha Grevich, Carmen C. Brewer, Michael Hoa, H. Jeffrey Kim, John A. Butman, Lori Broderick, Hal M. Hoffman, Ivona Aksentijevich, Daniel L. Kastner, Raphaela Goldbach-Mansky, and Andrew J. Griffith, “ NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy ,” Proceedings of the National Academy of Sciences, pp. 201702946, 2017. View at Publisher · View at Google Scholar
  • Sandra Hodge, Jennifer Treiberg, Sibylle Wilbert, Hai B Tran, Rhys Hamon, Eugene Roscioli, Greg Hodge, Hubertus Jersmann, Miranda Ween, Paul N Reynolds, and Arthur Yeung, “Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases.,” American journal of physiology. Lung cellular and molecular physiology, vol. 312, no. 5, 2017. View at Publisher · View at Google Scholar
  • Xiang Li, Xiaopei Yan, Yanli Wang, Jingjing Wang, Fang Zhou, Hong Wang, Weiping Xie, and Hui Kong, “NLRP3 Inflammasome Inhibition Attenuates Silica-Induced Epithelial to Mesenchymal Transition (EMT) in Human Bronchial Epithelial Cells,” Experimental Cell Research, 2017. View at Publisher · View at Google Scholar
  • Hai B Tran, Paul N Reynolds, Sandra Hodge, Hubertus Jersmann, Tung Thanh Truong, Rhys Hamon, Eugene Roscioli, Miranda Ween, Melissa R Pitman, Stuart M Pitson, and Greg Hodge, “Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD.,” PloS one, vol. 12, no. 11, 2017. View at Publisher · View at Google Scholar
  • Laura Denney, and Ling-Pei Ho, “The role of respiratory epithelium in host defence against influenza virus infection,” Biomedical Journal, 2018. View at Publisher · View at Google Scholar
  • Lixia Wang, Binshan Zha, Qiying Shen, Hongyun Zou, Cheng Cheng, Huimei Wu, and Rongyu Liu, “Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation,” Journal of Immunology Research, vol. 2018, pp. 1–8, 2018. View at Publisher · View at Google Scholar
  • Jeongah Song, Woojin Kim, Yong-Bum Kim, Bumseok Kim, and Kyuhong Lee, “Time course of polyhexamethyleneguanidine phosphate-induced lung inflammation and fibrosis in mice,” Toxicology and Applied Pharmacology, 2018. View at Publisher · View at Google Scholar