Immunolocalization of NLRP3 Inflammasome in Normal Murine Airway Epithelium and Changes following Induction of Ovalbumin-Induced Airway Inflammation
Figure 5
Increase of uric acid in BALFs (a) and cytokines IL-1β and TNF-α in sera (b) of OVA-treated mice, compared to saline-treated controls. (a) Box plot (showing median, interquartile range, and nonoutlier range) demonstrating that BALF uric acid levels are elevated in OVA-treated mice () compared to SAL mice (), (Kruskal-Wallis test). (b) Scatter plot of serum IL-1β versus TNF-α levels (pg/mL) in OVA-treated mice (open triangles, ) versus SAL-treated mice (closed triangles, ). High cytokine levels were only observed in the OVA-treated mouse group.
