Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable

Table 2

Agreement between two methods of vessel staining in both groups together.

	Mean, Collagen IV	Mean, Factor VIII	Mean of differences*	95% LoA^†
Number of vessels/mm Rbm	8.5	4.8	+3.7	−10.2, +17.6
Area of vessels/mm Rbm	803	357	+446	−995, +1887
MVS of Rbm vessels, μm²/number	98	73	+25	−143, +193
Number of vessels/mm² LP	313	356	−43	−333, +247
Area of vessels μm²/μm² of LP × 100	5.7	4.2	+1.5	−4.4, +7.4
MVS of LP vessels, μm²/number	212	133	+79	−184, +342

*Calculated as measurements with Collagen IV minus measurements with Factor VIII antibody.
^†LoA: limits of agreement (mean ±2 standard deviation).