Impact of Adiponectin Overexpression on Allergic Airways Responses in Mice

Figure 4

Leukocytes in BAL fluid (a) and blood (b), and BAL IL-13 (c), BAL eotaxin (d), and serum OVA-specific IgE (e) in wildtype (WT) and adiponectin transgenic (Adipo Tg) mice sensitized with ovalbumin (OVA) and challenged i.n. with OVA or PBS every week for 4 weeks. Data shown are mean ± SEM of 5–10 mice per group. ^∗𝑃<0.05 versus PBS challenged mice of the same genotype; ^#𝑃<0.05 versus WT mice with the same challenge. MAC: macrophages; NEU: neutrophils; EOS: eosinophils; LYM: lymphocytes; MON: mononuclear cells.

(a)

(b)

(c)

(d)

(e)